Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo

Article Abstract:

Complete coding regions of activin receptors cActR-IIA and -IIB cDNAs were subcloned to determine whether activin can induce mesoderm in chick embryo despite the absence of the hypoblast. Expression of the receptors was detected in the primitive streak by in situ hybridization, suggesting that these genes had been activated. In vitro assay for differentiation showed that primitive streak responds to activin by differentiating into a variety of mesodermal cell types. These results show that activin activates signaling pathways during various stages of development.

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Fate and plasticity of the endoderm in the early chick embryo

Article Abstract:

A fate map of the location and development of endoderm cells during gastrulation in chick embryo is presented.

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Fgf signaling negatively regulates nodal-dependent endoderm induction in zebrafish

Article Abstract:

The effects of fibroblast growth factor expression on endoderm and mesoderm induction are analyzed.

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