Article Abstract:
Examination of P element insertion into the intron of a Drosophila gene suggests a novel mechanism for the P(lacZ, rosy+) element-induced P element mutagenesis. Insertion of the P element into the intron of a gene in the proper orientation stimulates aberrant splicing and transcription termination, producing a mutant phenotype. A mRNA produced from the sequences existing within the element direct aberrant splicing and termination events constitutes 3' sequences from within the P(lac Z, rosy+) element and 5' sequences from the mutated gene.
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Article Abstract:
The combination of target P elements at homologous sites with transposase proteins as catalysts in the Drosophila melanogaster results in the formation of male recombination at very high rates. The male recombination is generally absent in the Drosophila species. The combination process produces these elements by the in situ deletion mechanism of certain insertion and deletion elements.
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Article Abstract:
Two mutant alleles which define the larval photokinesis A(lphA) gene are isolated and characterized in the Drosophila melanogaster. This gene is involved in the functioning of the lateral vision mechanisms in the Drosophila. The Drosophila larvae which express the lphA mutations are negatively photokinetic but respond to white light.
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