A tiny helper lightens the maternal load

Article Abstract:

A study revealing a surprising and elegant solution that could help to coordinately destroy a large number of maternal mRNAs at the mid-blastula transition of early animal embryogenesis is presented. Hence, an examination on fish that lacked the miRNA processing enzyme Dicer both maternally and zygotically is presented to demonstrate that miRNAs are essential for early morphogenesis of zebrafish embryos.

author: Weigel, Detlef, Izaurralde, Elisa
United States, Genetic aspects, Messenger RNA, Zebra fish, Zebra fishes, Blastula

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The bicoid morphogen papers (II): Account from Wolfgang Driever

Article Abstract:

A commentary is presented on the article 'Seeing Is Believing: The Bicoid Morphogen Gradient Matures' by Ephrussi, A and St. Johnston, D., appearing in the issue of 'Cell' dated January 23, 2004. The correlation between Bicoid concentration and the positional identity in the Drosophila blastoderm is discussed.

author: Driever, Wolfgang
Genetic research

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The bicoid morphogen papers (I) : Account from CNV

Article Abstract:

A commentary is presented on the article 'Seeing Is Believing: The Bicoid Morphogen Gradient Matures' by Ephrussi, A and St. Johnston, D., appearing in the issue of 'Cell' dated January 23, 2004. Issues pertinent to maternal mutants, cytoplasmic transplantation and bicoids are discussed.

author: Nusslen-Volhard, Christaine N.
Mutation (Biology), Mutation, Cytoplasm

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subjects list: Research, Morphogenesis
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