A stimulatory role for cGMP-dependent protein kinase in platelet activation

Article Abstract:

Research has been conducted on cGMP-dependent protein kinase. The role of this protein kinase in platelet activation has been investigated, and the results demonstrate that recombinant cGMP-dependent protein kinase's expression in reconstituted cell model can enhance von-Willebrand factor-induced platelet integrin activation.

author: Hofmann, Franz, Feil, Robert, Li, Zhenyu, Xi, Xiaodong, Gu, Minyi, Ye, Richard D., Eigenthaler, Martin, Du, Xiaoping
Germany, Protein kinases, Blood platelets, Integrins

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The PAS protein VIVID defines a clock-associated feedback loop that represses light input, modulates gating, and regulates clock resetting

Article Abstract:

Research has been conducted on the vvd gene which regulates light responses in Neurospora and encodes a member of the PAS/LOV protein superfamily. Results indicate that VVD contributes to the regulation within the Neurospora circadian system.

author: Loros, Jennifer J., Dunlap, Jay C., Heintzen, Christian
Statistical Data Included, Proteins, Circadian rhythms, Neurospora

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Lamins and disease: insights into nuclear infrastructure

Article Abstract:

Research has been conducted on the human diseases laminopathies which map to the gene encoding A-type lamins, LMNA. The review of the articles on the laminopathies with the unclear pathophysiological mechanisms is presented.

author: Wilson, Ketherine L., Zastrow, Michael S., Lee, Kenneth K.
Diseases, Nuclear research

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subjects list: United States, Analysis, Physiological aspects, Genetic aspects, Gene expression, Cell research, Cytological research
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