A simple method for detection of imprinting effects based on case-parents trios

Article Abstract:

The data from families in which marker genotypes are known for father mother and the affected offspring is used for developing a simple statistic for testing for imprinting effects. A simulation study is conducted to characterize the power of the parent-of-origin effects test statistic (POET) and its results have shown that it is proper to use the POET.

author: J.-Y. Zhou, Y.-Q. Hu, W.K. Fung
Genotype, Genotypes, Genomic imprinting

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LOD significance thresholds for QTL analysis in experimental populations of diploid species

Article Abstract:

This article presents a method to ascertain exact loci in a genome and its bearing in identifying the gene that affects quantitative traits. The author proposes the term "suggestive linkage" for an objective comparison of results across species in qunatitative trait loci analyses.

author: Ooijen, Johan W. Van
Netherlands, Statistical Data Included, Usage, Genetic markers, Statistical hypothesis testing

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On the methods for predicting the effective size of populations under selection

Article Abstract:

The author discusses two different approaches based on genetic drift and the rate of breeding to predict population size. Equations derived from the approaches are presented.

author: Nomura, Tetsuro
Japan, Genetic engineering, Inbreeding

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subjects list: Analysis, Linkage (Genetics), Research, Population biology
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