A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

Article Abstract:

Research shows that overexpression of the oncogene cyclin D1 is mediated by a transcription factor, C/EBPbeta/Nf-II6, and the protein C/EBPbeta regulates the genes affected by cyclin D1. Data demonstrate that C/EBPbeta protein is essential for the function of cyclin D1 oncogene.

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Physical and functional interactions between polo kinase and the spindle pole component Cut12 regulate mitotic commitment in S. pombe

Article Abstract:

Research has been conducted on Schizosaccharomyces pombe spindle pole component Cut12 which suppresses conditional lethal commitment defect. Results demonstrate that Cut12 associates with Plo1 in hybrid and immunoprescipitation assays.

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Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome

Article Abstract:

Research has been conducted on Yin6 , Schizosaccharomyces pombe Int6 homolog implicated in tumorigenesis. Results demonstrate that Yin6 binds and regulates proteasome in S. pombe.

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