A marker set for construction of a genetic map of the silver fox (Vulpes vulpes)

Article Abstract:

The genomic organizations genomic organizations of the silver fox (Vulpes vulpes) and the dog (Canis familiaris) are compared. Several single nucleotide polymorphisms (SNPs) are found when a sequence comparison of genes from tame and aggressive foxes is conducted. Canine genomic tools are utilized in developing a fox meiotic map and mapping behavioral traits in the fox due to a close relationship between the fox and dog.

author: Aguirre, G.D., Kukekova, A.V., Trut, L.N., Oskina, I.N., Kharlamova, A.V., Shikhevich, S.G., Kirkness, E.F., Achland, G.M.
Behavior, Dogs, Red fox, Genomics

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Feline adult beta-globin polymorphism reflected in restriction fragment length patterns

Article Abstract:

A study was conducted to analyze the molecular basis of feline adult beta-globin polymorphism reflected in restriction fragment length patterns. Southern blot analysis was carried out on the beta-globin gene region from 25 cats with 13 different high-performance liquid chromatography patterns. Results indicated an autosomal codominant mode of inheritance of the beta-globin chains with seven haplotypes.

author: Asakura, T., Giger, U., Henthorn, P.S., Kohn, B., Rajpurohit, Y., Reilly, M.P.
Globin genes, Domestic animals

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Inheritance, Biochemical Abnormalities, and Clinical Features of Feline Mucolipidosis II: The First Animal Model of Human I-Cell Disease

Article Abstract:

A domestic shorthair cat population was used to develop an animal model for the human lysosomal storage disease Mucolipidosis II, or I-cell disease, to use in therapeutic intervention and pathogenesis research. Mode of inheritance, lysosomal enzyme activities, and radiographic and clinical features were found to be homologous with I-cell disease in humans.

author: Wang, P., Mazrier, H., Van Hoeven, M., Knox, V.W., Aguirre, G.D., Holt, E., Wiemelt, S.P., Sleeper, M.M., Hubler, M., Haskins, M.E., Giger, U.
Usage, Physiological aspects, Diseases, Animal models in research, Animal research models, Mucolipidoses

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subjects list: Research, Genetic aspects, Domestic cats, Cats
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