A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling

Article Abstract:

Research has been conducted on Spen proteins which regulate transcriptional effector expression in diverse signaling pathway. Results demonstrate that these proteins play important role in the transcriptional repression complex in both nuclear receptor and Notch signaling pathways.

author: Ariyoshi, Mariko, Schwabe, John W. R.
United Kingdom, Genetic regulation, Gene expression

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Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing

Article Abstract:

Research has been conducted on Sm proteins which form ring-shaped Sm core. The authors have characterized Lsm11 as a Sm-like protein, and report that the long N-terminal part of this protein mediates histone mRNA 3'-end cleavage.

author: Luhrmann, Reinhard, Pillai, Ramesh S., Grimmler, Matthias, Meister, Gunter, Will, Cindy L., Fischer, Utz, Schumperli, Daniel
Germany, Switzerland, Histones, Messenger RNA

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Transcription from an upstream promoter controls methylation signaling from an inverted repeat of endogenous genes in Arabidopsis

Article Abstract:

Research has been conducted on Arabidopsis methylated PAI tryptophan biosynthetic genes. The authors demonstrate that PAI transcript initiates at the unmethylated promoter which is upstream of the inverted repeat PAI genes.

author: Bender, Judith, Melquist, Stacey
United States, Arabidopsis, Methylation, DNA replication

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subjects list: Analysis, Physiological aspects, Genetic aspects, Proteins, Genetic transcription, Transcription (Genetics), RNA, Genetic research
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