A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans

Article Abstract:

Research has been conducted on coiled-coil protein LIN-5 from Caenorhabditis elegans. The authors describe the related proteins G protein regulator 1 (GPR-1) and GPR-2 which depend on LIN-5 protein for localization to the spindle and cell cortex.

author: Srinivasan, Daylan G., Fisk, Rigely M., Xu, Huihong, Van Den Heuvel, Sander
Caenorhabditis elegans, G proteins

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Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional division

Article Abstract:

Research has been conducted on meiotic chaismata. The authors describe the chromosomal processes related to meiotic chaismata's formation and function, and they report that double-strand breaks promote events beyond recombination.

author: Kleckner, Nancy, Zickler, Denise, Storlazzi, Aurora, Tesse, Sophie, Gargano, Silvana, James, Francoise
Italy, France, Genetic recombination, Meiosis

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The Fanconi road to cancer

Article Abstract:

The author discusses the studies on cloned Falconi Anemia genes' FA/BRCA pathway. The topics of interest include the role of this pathway in homologous recombination repair.

author: D'Andrea, Alan D.
Causes of, Gene mutations, Gene mutation, DNA repair, Cancer, Genetic disorders

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subjects list: United States, Analysis, Genetic aspects, Genetic regulation, Chromosomes, Genetic research, Physiological aspects
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