Article Abstract:
A DNA replication-arrest site RTS1 has been found to regulate imprinting by specifying the direction of replication at mat1 in Schizosaccharomyces pombe. The TRS1 barrier is shown to be a polar terminator of replication that optimizes imprinting by controlling the direction of replication at mat1. In higher eukaryotes there may be a more general role in development/differentiation, regulating the direction of DNA replication at important loci.
User Contributions:
Comment about this article or add new information about this topic:
Article Abstract:
The article explores the molecular level of a DNA replication during meiosis in fission yeast. Checkpoint mechanisms that operate in meiotic cells and not in mitotic ones, and the difference between meiotic and mitotic cell cycles, are discussed.
User Contributions:
Comment about this article or add new information about this topic:
Article Abstract:
De novo nucleosome assembly and the proteins involved are discussed in this review article. Functions in the maintenance of chromosome integrity are covered.
User Contributions:
Comment about this article or add new information about this topic: