2,3,7,8-Tetrachlorodibenzo-p-dioxin affects fluctuating asymmetry of molar shape in mice, and an epistatic interaction of two genes for molar size

Article Abstract:

The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the fluctuatin asymmetry (FA) of molar shape in mice, which is produced from an intercross between two inbred strains, is examined. The results have shown that although TCDD might affect the expression of some genes governing the development of molars in mice, the FA of molar size and shape is not particularly sensitive indicator of this effect.

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Genome-wide characterisation of Hepatitis B mutations involved in clinical outcome

Article Abstract:

HBV genomes of Hepatitis B were investigated to study the different states of the disease such as acute, chronic and fulminant infection and the outcome of such infection. Results suggest that the genetic composition of the infective HBV strains is a major determinant of clinical outcome and disease outcome can be predicted to a large extent with a limited number of host and viral factors.

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Genetics, development, and paleontology interlock

Article Abstract:

The enamel knot inhibitor, ectodin, an inhibitor of bone morphogenetic proteins (BMPs) is described and it is shown that expressing ectodin, is critical for proper morphogenesis of mammalian tooth crowns. It is confirmed that the potential of teeth as a model system to synthesize evolutionary biology in a way that Genetics, Paleontology, and Evolution could not.

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